John Birch, Surgeon to St. Thomas's Hospital, 1815, referring to the excuses made by the Jennerians for vaccine failure.

It cannot be meant to class Mr. Wachsell, Apothecary to the Small-pox Hospital, or Mr. Ring, the Accoucheur, among ignorant and equivocal practitioners; and yet from the patients vaccinated by these two persons, I could bring instances of more failures, more deaths, and more diseases than have occurred in the practice of any other two persons who have come within my knowledge.

And again, were an architect to undertake to build an edifice which should be firm in its foundations, all its rooms wind and water tight, and such as might be inhabited with perfect security; if before the edifice were well finished, the foundations were discovered to be rotten; and if in less than seven years, several apartments had fallen in and killed those who occupied them, while in a great number of rooms the wind or rain was continually beating in, could I be blamed for declaring that the architect had broken his contract, and that the edifice ought no longer to be inhabited? Certainly not. Why then am I to be told that I am acting perversely when I remonstrate against the practice of cow-pox? for such an edifice as I have described, so rotten in its foundations, so ill built, so ruinous, is vaccination.—An Appeal to the Public on the Hazard and Peril of Vaccination, otherwise Cow-pox, by the late John Birch, Esq., together with his Serious Reasons for uniformly objecting to Vaccination; and other Tracts by the same Author. 3rd Edition. London, 1817.