Future Research

As this project is based on laboratory work in New Zealand the future research for this project is outlined below:

In this project frozen samples brought back this season will be used to repeat the purification procedures developed after the 1983/84 season. It is hoped that the experiments giving the enthalpy of activation for the glutathione-s-transferase will be repeated and attempts will be made to characterize this and the other glutathione-s-transferases present in D.mawsoni.

The glutathione-s-transferases of the fish Geniagnus monopterygius will be purified and characterized as a comparative species. It is hoped sufficient enzyme will be obtained to gain an enthalpy of activation with as least one of the isoenzymes.

Rat glutathione-s-transferases will be used to look at variation within one animal as opposed to variation between species. The glutathione-s-transferases of rat are highly characterized making it a suitable candidate for study.